The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor.

Department of Pharmacological Sciences, University of Milan, Milan 20133, Italy Autonomic Neuroscience Institute, Royal Free & University College Medical School, Rowland Hill Street, Hampstead, London NW3 2PF, UK IRIBHM and Department of Medical Chemistry, Erasme Hospital, University Libre Bruxelles, Brussels B1070, Belgium Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK Molecular Pharmacology, Inspire Pharmaceuticals Inc., Durham, NC 27703, USA Department of Physiology and Pharmacology, University of Strathclyde, Glasgow G4 0NR, UK Department of Bioquimica, Universidad Complutense de Madrid, Madrid 28040, Spain INSERM U.311, EFS-Alsace, Strasbourg 67065, France Laboratory of Bioorganic Chemistry, NIDDK, NIH, Bethesda, MD 20892-0810, USA Department of Biochemistry, University of Missouri, Columbia, MO 65212, USA